|
KMID : 0356619950100030273
|
|
Journal of Korean Society of Endocrinology
1995 Volume.10 No. 3 p.273 ~ p.277
|
|
|
A Case of Nesidioblastosis in Adult with Hyperinsulinemic Hypoglycemia
|
|
김홍규
민영주/박중열/송영기/홍성관/이기업/김기수/한덕종/이호정
|
|
|
Abstract
|
|
|
Nesidioblastosis is a primarily childhood disease which is often associatd with hyperinsulinemic hypoglycemia. It is very rarely found in adults. Only a few well documented cases are found in the world literature. The authors have recently
experienced a
case of nesidioblastosis in an adult. A 55-year-old man was admitted due to repeated episodes of reversible loss of consciousness. Hyperinsulinemic hypoglycemia was documented. Under the presumptive diagnosis of insulinoma, localization
procedures
were
done but no definite tumor was found. Only suspicious gradient in insulin concentration was found around the head of pancreas by percutaneous transhepatic portal venous sampling. Exploratory laparotomy was performed and Whipple's operation was
done.
Seventy percent of proximal pancreas was removed. Histomorphometric study of the resected specimen revealed uneven graded hyperplasia of the islet cells with the most profuse hyperplasia in the head region and progressive decrease in the degree
of
hyperplasia to the body and tail. The patient remains euglycemia until 6 months after operation since immediate postoperative period and can tolerate 24 hour fasting without any medication(J Kor Soc Endocrinol 10:273~277, 1995).
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|